A 45-year-old male presents to the clinic with fatigue, unexplained bruising, and frequent nosebleeds

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A 45-year-old male presents to the clinic with fatigue, unexplained bruising, and frequent nosebleeds. Blood tests reveal leukocytosis, anemia, and thrombocytopenia. A bone marrow biopsy confirms the diagnosis of acute myelogenous leukemia (AML). Answer all questions listed below and cite evidence-based sources to support your initial post and responses.  Which genetic mutations are commonly associated with the disease?  Why is the patient presenting with the specific symptoms described?  Discuss the pathophysiological mechanisms of the disease in detail.  What do the blood test results tell us about the disease and disease progression?

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