Kayla· Age: 35· Kayla is seeking genetic counseling for muscular dystrophy.
Emily· Age: 40· Emily is seeking karyotype analysis
Please use the below chart for navigation to the tests.
Scenario 1 – Pedigree Analysis (Page 2)
Scenario 2 – Karyotype (Look on Page 5)
Relationship between 1 and 2
Gender of Fetus
Relationship between 1 and 5
Relationship between 1 and 10
Chromosomal Combination Result
Relationship between 6 and 7
Relationship between 4 and 5
Relationship between 5 and 8
Relationship between 8 and 10
Relationship between 1 and 3
Chances mother is a carrier
Chances Kayla is a carrier
Chances Kayla passes the syndrome to male child
If Kayla is a carrier, what are chances of having an affected child?
If Kayla is not a carrier, what are chances of having an affected child?
Scenario One – Our patient seeks genetic counseling
Kayla has a family history of Duchenne muscular dystrophy (DMD), which is a sex-linked trait. The patient wishes to know her risk of having an affected child. Her grandmother was a known carrier. DMD is an inherited disorder that involves progressive muscle weakness. It affects approximately 1 in 3500 male births worldwide and is inherited in an X-linked recessive pattern.